Rose Cotter (SOSIE BACON) is a doctor at a New Jersey emergency psychiatric unit who went into that line of work stemming from her mother's suicide when Rose was 10-years-old. When a new patient, Laura Weaver (CAITLIN STASEY) -- who claims to be haunted by sinister forces she can't fully explain -- kills herself in front of Rose, the doctor's life quickly begins to unravel.

That ends up putting a strain on her relationship with her live-in fiancé, Trevor (JESSIE T. USHER), and further distances her from her older sister, Holly (GILLIAN ZINSER). When she realizes she's caught in some sort of supernatural chain, she turns to her police detective ex, Joel (KYLE GALLNER), for help in trying to figure out how to extricate herself from that.