It's the 1950s and Frank (LEONARDO DiCAPRIO) and April Wheeler (KATE WINSLET) seem to be like most any other married couple living in the Connecticut suburbs with two young kids. While April cares for Jennifer (RYAN SIMPKINS) and Michael (TY SIMPKINS) and has pretty much given up her dreams of being an actress, Frank works in Manhattan for a business machine company alongside the likes of Jack Ordway (DYLAN BAKER) and others who obviously don't have much passion for their jobs. Yet, Frank certainly has the latter for office secretary Maureen Grube (ZOE KAZAN) with whom he's having an affair.
And that's because his marriage to April is anything but rosy. She's unhappy that her life on Revolutionary Road is obviously headed toward a dead end, and the couple often engage in heated arguments, unlike their neighbors and friends, Millie (KATHRYN HAHN) and Shep Campbell (DAVID HARBOUR). The latter obviously has a thing for April, but nothing has come of that, and April can't stand the thought of living a life like the smiling and subservient Millie.
Accordingly, she proposes that she and Frank move to France and start anew. That idea takes their real estate agent, Helen Givings (KATHY BATES), by surprise, as she hopes that the young couple might help her and her husband, Howard (RICHARD EASTON), re-socialize their adult son, John (MICHAEL SHANNON), a once promising mathematician sidelined by mental illness.
Yet, as they prepare for an overhaul of their lives that April hopes will save their marriage, a number of unexpected developments, including from Frank's big boss, Bart Pollack (JAY O. SANDERS), threaten to derail their plans and hopes for newfound happiness.