John Brennan (RUSSELL CROWE) is an English professor and family man, happily married to businesswoman Laura (ELIZABETH BANKS) and proud and caring father to their young son Luke (TY SIMPKINS). The morning after a night out with friends, however, their life together is turned upside down when Laura is unexpectedly arrested for the murder of her boss. With all of the available evidence pointing at her, she ends up convicted and imprisoned for the crime.
That puts a great deal of strain on John as he tries to continue raising Luke as normally as possible, but with the boy shunning his mother in prison and following her suicide attempt, he's desperate for a solution. He thinks he finds it in a convict (LIAM NEESON) who's escaped from the joint numerous times and gives John various pointers about what's necessary to pull off such an act.
Anytime he's not with Luke, or when the boy is off with his grandparents, George (BRIAN DENNEHY) and Grace (HELEN CAREY), or at a birthday party thrown by the parent, Nicole (OLIVIA WILDE), of one of Luke's classmates, John is plotting his course of action, including doing recon at the prison, trying to get fake passports and such.
As he prepares and then sets his plan into motion -- even surprising Laura with it upon springing it on her -- John must contend with various expected and unexpected developments, including the likes of cops Det. Quinn (JASON BEGHE) and Lt. Nabulsi (LENNIE JAMES) ending up on his trail, determined to prevent him from leaving Pittsburg and fleeing to another country.