In the near future, video game players control their on-screen avatars via mind control, but their game characters are real people, thanks to the work of Ken Castle (MICHAEL C. HALL). His pioneering advances in the industry have made him a billionaire and subject of lots of press coverage, including by talk show host Gina Parker Smith (KYRA SEDGWICK) who does a story on his achievements.
First, there was Society, where everyday players control actors in a game of interacting with others. But with the high interest in violent video games, Castle created Slayers, a first-person shooter game where prisoners, such as Freak (JOHN LEGUIZAMO), have volunteered to be controlled as soldiers. If they manage to live through 30 games, they're granted their freedom, and Kable (GERARD BUTLER) is the only one who's gotten close with only a few to go.
Controlled by 17-year-old high-tech gamer Simon (LOGAN LERMAN), Kable is a seemingly non-stoppable killing machine, but unlike the others, he didn't volunteer for the post, just like four years earlier when he was used in a test that resulted in him unwillingly murdering another man. Now that he's close to getting his freedom, Castle has sent in Hackman (TERRY CREWS), a hulking killer who reportedly doesn't have the physical brain control implant and thus is a free agent of sorts whose only desire is to dispatch Kable from the game.
As the reluctant fighter tries to gain his freedom so that he can be reunited with his wife, Angie (AMBER VALLETTA) -- an actor in the Society game where she's used as a sexpot puppet -- as well as their young daughter, Delia (BRIGHID FLEMING), others are working to insure both his freedom and an end to Castle's empire. Consisting of leader Humanz Brother (LUDACRIS) and his assistants, Humanz Dude (AARON YOO) and Trace (ALISON LOHMAN), they repeatedly attempt to infiltrate Castle's network.
With Hackman intent on killing Kable and Castle counting his mounting piles of cash, Kable does what he can to survive the last few games and get revenge on those who've wrongly imprisoned him.