Quarterback Nick (ERIC CHRISTIAN OLSEN) and wide receiver Shawn (NICHOLAS D'AGOSTO) are the star players on the Gerald R. Ford High Tigers football team. When they hear that foul-mouthed Coach Byrnes (PHILIP BAKER HALL) will be taking the team to El Paso rather than a place they imagine will be filled with lots of scantly clad women, they're disappointed. But opportunity comes knocking when they realize that if they join the cheerleading squad they'll likely be the only straight guys surrounded by hundreds of athletic and hopefully willing young women at a cheer camp.
Despite the protests of squad leader Carly (SARAH ROEMER) who sees through their scheme, Nick and Shawn -- with the help of the latter's younger but too wise for her years sister, Poppy (JULIETTE GOGLIA) -- are allowed to join since they might help the girls finish somewhere higher than last place at a championship meet.
Accordingly, the guys join them in traveling to the cheer camp lead by Coach Keith (JOHN MICHAEL HIGGINS) and his wife, Diora (MOLLY SIMS). While stuck rooming with the likes of Brewster (ADHIR KALYAN) and Downey (JAKE SANDVIG), the guys quickly try to hook up with as many female cheerleaders as possible. But while Nick becomes obsessed with conquering Diora who wants nothing to do with him, Shawn becomes drawn to Carly.
However, since she's dating pre-med student, Rick (DAVID WALTON), and must contend with a rival cheerleading squad led by the condescending Gwyneth (ANNALYNNE McCORD), Carly only sees Shawn as a friend. From that point on, the guys end up derailing their own plans as they decide to stick around and try to help their cheerleading squad win.