Dave (VINCE VAUGHN) and Ronnie (MALIN AKERMAN) are like many a middle-aged married couple in trying to balance work and raise kids. They're mostly complacent with their arrangement, even if she isn't happy that he doesn't seem to care one way or another about her home remodeling choices.
They're better off than their friends, however, such as Shane (FAIZON LOVE) who's divorced from Jennifer (TASHA SMITH) and is now dating 20-year-old Trudy (KALI HAWK). High school sweethearts Joey (JON FAVREAU) and Lucy (KRISTIN DAVIS) can't stand each other, but it's Jason (JASON BATEMAN) and Cynthia (KRISTEN BELL) who've announced they're likely going to get divorced, mostly stemming from their inability to conceive.
Realizing the strain that's put on their relationship, they're willing to give it one last shot, and want to attend a relationship program at Eden, a tropical resort split into two islands where singles mingle on one and couples examine and try to invigorate their relationships on the other.
The only problem is that they can't afford the program, but could in a group rate if they can get their friends to go along. Promised that they won't have to attend the workshops and such, the others agree, and soon they're in the company of host Stanley (PETER SERAFINOWICZ) who calmly informs all of them that by attending, they must go through the program.
Accordingly, they're introduced to "couples whisperer" instructor Marcel (JEAN RENO), various therapists who work with them individually, and uninhibited yoga instructor Salvadore (CARLOS PONCE). As the sessions proceed, the various couples learn a thing or two about themselves and each other.