It's 1925 and Jimmy "Dodge" Connelly (GEORGE CLOONEY) is the middle-aged star of the Duluth Bulldogs, one of a few struggling teams in the new pro football league. Due to little public interest and thus low attendance despite the hulking presence of high school player Big Gus (KEITH LONEKER) who's recently joined them, his team is the latest to fold, which is something of an insult considering that college games routinely draw huge crowds.
When he hears that more than 40,000 people attended a recent Princeton game -- mainly to see its star and famed WWI hero Carter "The Bullet" Rutherford (JOHN KRASINSKI) -- Dodge sets up a meeting with Carter's agent, CC Frazier (JONATHAN PRYCE). Promising Carter (and thus CC) a huge payday if he goes pro, Dodge convinces him to join his newly resurrected team, and makes sure that boozing sports reporter Suds (STEPHEN ROOT) gets the story right so as to garner public interest.
Dodge isn't the only one interested in Carter, however, as Chicago Daily Tribune reporter Lexi Littleton (RENÉE ZELLWEGER) has been promised a promotion by her editor, Harvey (JACK THOMPSON), if she can prove allegations that Carter's war hero status is inaccurate. Feisty and armed with quick come-backs, she and Dodge immediately clash, although there's obvious budding romantic chemistry between them lurking just beneath the surface. Yet, and from that point on, Dodge must contend with Carter seemingly sweeping her off her feet, all while also becoming the new star of the team.