David (LUKE WILSON) and Amy Fox (KATE BECKINSALE) are an unhappily married couple literally and figuratively headed on their way for a divorce following the untimely death of their young son sometime in the past. While driving to some small remote town at night, David ends up getting lost, which is also when they develop car problems. After breaking down, they hike back to the Pinewood Motel in hopes of finding a mechanic, but with it being so late, any such garage near or far is closed for the night.
The somewhat odd motel manager, Mason (FRANK WHALEY), informs them that he has rooms, and with no better option, the couple reluctantly agrees to stay there until morning. Seedy, old, and dirty, their motel room isn't desirable, which also holds true for the limited in-room entertainment options.
With no TV reception, David pops in an unmarked videotape only to discover that it appears to be a snuff film taped in their room. With subsequent tapes proving to be the same thing but with different victims, the couple becomes quite concerned, especially following a bout of some unseen person calling their room and loudly pounding on the door.
Realizing they're being watched and now trapped in the room after trying to make a run for it only to be chased back by some masked men, David and Amy do what they can to survive, knowing full well that they're the stars of the latest snuff film production.