Directors Quentin Tarantino and Robert Rodriguez provide a double-feature bit of homage to exploitation films of the past.
In "Planet Terror," Cherry (ROSE McGOWAN) is a go-go dancer who wants a change in her life. She unexpectedly gets it not long after meeting her ex, Wray (FREDDY RODRIGUEZ), at a barbeque joint run by JT (JEFF FAHEY) where a young woman, Tammy (STACY "FERGIE" FERGUSON), is having car troubles.
She's the former lover of anesthesiologist Dakota Block (MARLEY SHELTON) whose marriage to fellow physician Bill (JOSH BROLIN) is on the rocks. The various strained relationship issues fall by the wayside, however, when an experimental gas created by biochemical engineer Abby (NAVEEN ANDREWS) for military man Lt. Muldoon (BRUCE WILLIS) develops bad side effects. Covering anyone it touches with horrendous boils, the gas also seems to turn the afflicted into zombies.
With Sheriff Hague (MICHAEL BIEHN) and his men on the case, those fortunate enough not to be infected try to avoid and must battle the zombies who want to infect and/or kill them.
In "Death Proof," Jungle Julia (SYDNEY TAMIIA POITIER) is an Austin, Texas deejay who's out celebrating with her friends Shanna (JORDAN LADD) and Arlene (VANESSA FERLITO). They end up in a bar where weathered stunt driver Stuntman Mike (KURT RUSSELL) has agreed to give a ride to Pam (ROSE McGOWAN). Belying his friendly demeanor, he proceeds to terrorize all of them.
Some time later, New Zealander ZoŽ (ZOň BELL) has joined friends Kim (TRACIE THOMS), Abernathy (ROSARIO DAWSON), and Lee (MARY ELIZABETH WINSTEAD) during their hiatus from some filmmaking. ZoŽ is desirous of taking an old Dodge Challenger out for a spin, hoping to perform a stunt with Kim who happens to be a stunt driver. With Abernathy in tow and Lee left back with the owner, the women set out for some driving fun. Their plans are shortchanged, however, when Stuntman Mike decides to have some deadly fun with them, unaware of their resolve to get even.