Edward Malus (NICOLAS CAGE) is a California motorcycle cop still haunted by a past event where he was unable to save a young girl and her mother trapped in a burning car. Physically and mentally harmed from the incident, he now self-medicates himself, much to the concern of fellow cops such as Pete (MICHAEL WISEMAN). But he finds a purpose in life when he receives a letter from his ex-fiancée Willow (KATE BEAHAN) who left him long ago to return to her paganish commune on the isolated island known as Summersisle. She states that her daughter, Rowan (ERIKA SHAYE GAIR), has disappeared and asks for Edward's help in finding her.
Accordingly, he sets out for the remote isle in the Pacific Northwest, but must bribe a seaplane pilot to take him there. Outsiders are not welcome to the place where the men are not only severely outnumbered by the likes of the women -- including Sister Rose (MOLLY PARKER), Sister Thorn (MOLLY PARKER), Sister Honey (LEELEE SOBIESKI) and Sister Beech (DIANE DELANO) -- but are also completely subservient to them and their leader, Sister Summersisle (ELLEN BURSTYN).
After being reunited with Willow, Edward sets out on his investigation to find Rowan, although he gets little cooperation from the women including Dr. Moss (FRANCES CONROY) who also serves as the village's photographer, taking photos of children for annual harvest rituals.
With Rowan's photo missing and hearing that the harvest associated with her was one of the worst on record, Edward does everything he can to try to find the girl, especially when he becomes increasingly suspicious that the inhabitants may be preparing her for a pagan-like ritual of death and rebirth involving someone known as the Wicker Man.