Jazmin Biltmore (MO'NIQUE) is a plus-size single woman who lives with her super-slim, but buxom cousin Mia (JOYFUL DRAKE) and works at a department store with her best friend and fellow overweight woman Stacey (KENDRA C. JOHNSON) alongside the highly effeminate Ramón (FELIX PIRE). Jazmin dreams of one day showing her fashion designs for women her size to clothing line buyer Robert Myer (ERIC ROBERTS), but her immediate boss Richard "Dick" Eckhard (JACK NOSEWORTHY) doesn't think she has the talent or abilities.
In a world where only the trim are considered beautiful and desirable, Stacey and especially Jazmin feel completely out of place, and their love lives have been anything but active of recent. That's about to change when Jazmin wins a spa package at a luxurious resort and soon she, Stacey and Mia set off for it. While they still encounter the same attitudes from others about their bodies, they get some unexpected but quite welcome attention from several Nigerian doctors, Tunde (JIMMY JEAN-LOUIS), Akibo (GODFREY) and Godwin (DAYO ADE), who are in town for a medical conference.
To Tunde and his friends, Jazmin and Stacey are the ideal sized women, while Mia seems malnourished and undesirable. The two women can't believe what's happening, but quickly accept the favorable attention. From that point on, and as the men try to help the women break out of their self-imposed social shells, Jazmin must contend with her contrasting views of herself and her place in the world, all while hoping to make a scene in the fashion biz.