Nearly a decade after the human resistance movement of the future sent a reprogrammed cyborg, the Terminator (ARNOLD SCHWARZENEGGER), to protect their future savior and leader, their machine foes have now sent a more advanced terminator unit, the T-X (KRISTANNA LOKEN) to kill John Connor (NICK STAHL).
An android that looks like an anatomically correct woman, the T-X can assume the shape of anything she touches and control any machine, and has been programmed to kill John and various other future lieutenants, such as veterinarian Kate Brewster (CLAIRE DANES).
The resistance, however, has again sent one of the older terminator units (ARNOLD SCHWARZENEGGER) back in time to the present to protect John and Kate from the T-X. As the pending nuclear Armageddon approaches, John and Kate, with the help of the Terminator, try to avoid the repeated attacks of the T-X unit and race to save humanity.