Alex Browning (DEVON SAWA) is an everyday student who's arrived at JFK to fly off to Paris with his high school French class. Seeing all sorts of nebulous signs of pending doom and then experiencing a realistic vision of the plane crashing, Alex freaks out before the plane even leaves the gate.
When fellow student and resident jerk, Carter (KERR SMITH), suddenly goes after Alex for disrupting the beginning of their trip, the two of them, along with Alex's best friend Tod (CHAD E. DONELLA), Carter's girlfriend Terry (AMANDA DETMER), fellow students Billy (SEANN WILLIAM SCOTT) and Clear (ALI LARTER) and one of their teachers, Ms. Lewton (KRISTEN CLOKE) find themselves back at the gate watching their plane take off.
All of them are understandably mad or concerned about Alex's actions and their missing the flight, that is until the plane explodes in midair, killing everyone on board. While their immediate reaction is shock and grief over what's just transpired, arriving FBI agents Weine (DANIEL ROEBUCK) and Schreck (ROGER GUENVER SMITH) become suspicious of Alex's premonition of the explosion.
Even so, no charges are filed and time passes by. Back at school, the survivors dedicate a memorial to those who perished, but they've all been changed by the turn of events. That's particularly true for Alex since everyone now believes him to be a freak, especially when the ensuing deaths of those who survived causes him to come up with the theory that Death wants to settle the score for being cheated out of earlier taking their lives. As the group's numbers begin to diminish, the survivors do what they can to avoid Death once more.