A one-time contender for the middleweight boxing title of the 1960s, Rubin "Hurricane" Carter (DENZEL WASHINGTON) is a man who turned his life around after spending more than half of his troubled childhood and early adult years being incarcerated in some fashion.
Although his future seemed bright, one night in 1966 changed all of that. Framed by Vincent Della Pesca (DAN HEDAYA) -- a bad cop who's had it out for him for years - for several murders he didn't commit, Carter and another innocent man, John Artis (GARLAND WHITT), are sentenced to several consecutive life terms. Despite various attempts to appeal his conviction, Rubin eventually realizes he may never get out, and even tells his wife, Mae Thelma (DEBBI MORGAN), to divorce him for the good of both.
Things change, however, years later when a young man, Lesra Martin (VICELLOUS REON SHANNON), picks up Carter's several year old novel, "The Sixteenth Round," and becomes fascinated by the man and his plight. Cared for and tutored by a trio of Canadians, Lisa (DEBORAH KARA UNGER),
Sam (LIEV SCHREIBER), and Terry (JOHN HANNAH) who rescued him from a dead end home life and are preparing him for college, Lesra begins corresponding with the now reclusive Rubin.
Soon Lesra and his Canadian mentors become good friends with Rubin, but when another appeal is lost, the former boxer decides that all hope is lost. Yet, Lesra and the others persevere, and despite the long odds and Della Pesca's intimidating ways, they continue in their battle to bring about Carter's freedom.